早稲田大学 理工学術院 基幹理工学部 電子物理システム学科 バイオマイクロシステム 森本雄矢研究室

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Publication

論文

2024

  1. Harnessing the Propulsive Force of Microalgae with Microtrap to Drive Micromachines
    (* equal contribution) Haruka Oda*, Naoto Shimizu*, Yuya Morimoto, and Shoji Takeuchi
    Small, vol. 20, 2402923, 2024
  2. Pillar electrodes embedded in the skeletal muscle tissue for selective stimulation of biohybrid actuators with increased contractile distance
    Tingyu Li, Minghao Nie, Yuya Morimoto, and Shoji Takeuchi
    Biofabrication, vol. 16, 035022, 2024
  3. “Biohybrid bipedal robot powered by skeletal muscle tissue”
    Ryuki Kinjo, Yuya Morimoto, Byeongwook Jo, and Shoji Takeuchi
    Matter, vol. 7 (3), pp. 948-962, 2024

2023

  1. “Biohybrid tensegrity actuator driven by selective contractions of multiple skeletal muscle tissues”
    Kazuma Morita, Yuya Morimoto, and Shoji Takeuchi
    Biofabrication, vol. 15, 045002, 2023
  2. “Real-time quantitative characterization of ion channel activities for automated control of a lipid bilayer system”
    Kazuo Ogishi, Toshihisa Osaki, Hisatoshi Mimura, Izumi Hashimoto, Yuya Morimoto, Norihisa Miki, and Shoji Takeuchi
    Biosensors and Bioelectronics, vol. 237, 115490, 2023
  3. “Co-culture system of human skin equivalents with mouse neural spheroids”
    Satoshi Inagaki, Yuya Morimoto, Ikuo K. Suzuki, Kazuo Emoto and Shoji Takeuchi
    Journal of Bioscience and Bioengineering, vol. 136 (3), pp. 239-245, 2023

2022

  1. “Microfluidic Device to Manipulate 3D Human Epithelial Cell-Derived Intestinal Organoids”
    (* equal contribution) Miki Matsumoto*, Yuya Morimoto*, Toshio Sato, and Shoji Takeuchi
    Micromachines, vol. 13 (12), 2082, 2022
  2. “Living skin on a robot”
    Michio Kawai, Minghao Nie, Haruka Oda, Yuya Morimoto, and Shoji Takeuchi
    Matter, vol. 5 (7), 2190-2208, 2022
  3. “3D-printed centrifugal pump driven by magnetic force in applications for microfluidics in biological analysis”
    Byeongwook Jo, Yuya Morimoto, and Shoji Takeuchi
    Advanced Healthcare Materials, vol. 11, 2200593, 2022
  4. “Functional analysis of human brain endothelium using a microfluidic device integrating a cell culture insert”
    Shigenori Miura, Yuya Morimoto, Tomomi Furihata and Shoji Takeuchi
    APL Bioengineering, vol. 6 (1), 016103, 2022
  5. “3D printed microfluidic devices for lipid bilayer recordings”
    Kazuto Ogishi, Toshihisa Osaki, Yuya Morimoto, and Shoji Takeuchi
    Lab on a Chip, vol. 22, 890-898, 2022

2021

  1. “Skeletal muscle-adipose cocultured tissue fabricated using cell-laden microfibers and a hydrogel sheet”
    Byeongwook Jo, Yuya Morimoto, and Shoji Takeuchi
    Biotechnology and Bioengineering, vol. 119 (2), 636-643, 2021
  2. “A Cylindrical Molding Method for the Biofabrication of Plane-Shaped Skeletal Muscle Tissue”
    (* equal contribution) Minghao Nie*, Ai Shima*, Kenta Fukushima*, Yuya Morimoto, and Shoji Takeuchi
    Micromachines, vol. 12 (11), 1411, 2021
  3. “Microfluidic system for applying shear flow to endothelial cells on culture insert with collagen vitrigel membrane”
    Yuya Morimoto, Shogo Nagata, Miki Matsumoto, Keisuke Sugahara, Shigenori Miura and Shoji Takeuchi
    Sensors and Actuators B: Chemical, vol. 348, 130675, 2021
  4. “Cell-based biohybrid sensor device for chemical source direction estimation”
    (*equal contribution) Haruka Oda*, Kazunori Kihara*, Yuya Morimoto, Sho Takamori, and Shoji Takeuchi
    Cyborg and Bionic Systems, vol. 2021, 8907148, 2021
  5. “Formation of contractile 3D bovine muscle tissue for construction of millimetre-thick cultured steak”
    (*equal contribution) Mai Furuhashi*, Yuya Morimoto*, Ai Shima, Futoshi Nakamura, Hiroshi Ishikawa and Shoji Takeuchi
    npj Science of Food, vol. 5, 6, 2021

2020

  1. “Biohybrid robot with skeletal muscle tissue covered with a collagen structure for moving in air”
    Yuya Morimoto, Hiroaki Onoe, Shoji Takeuchi
    APL Bioengineering, vol. 4 (2), 026101, 2020
  2. “A dynamic microarray device for pairing and electrofusion of giant unilamellar vesicles”
    Keisuke Sugahara, Yuya Morimoto, Sho Takamori, Shoji Takeuchi
    Sensors and Actuators B: Chemical, vol. 311, 127922, 2020

2019

  1. “Biohybrid device with antagonistic skeletal muscle tissue for measurement of contractile force”
    Yuya Morimoto, Hiroaki Onoe, Shoji Takeuchi
    Advanced Robotics, vol. 33 (5), pp. 208-218, 2019
  2. “Centrifuge-based step emulsification device for simple and fast generation of monodisperse picoliter droplets”
    Dong-Chel Shin, Yuya Morimoto, Jun Sawayama, Shigenori Miura, Shoji Takeuchi
    Sensors and Actuators B: Chemical, vol. 301, 127164, 2019
  3. “Temporal observation of adipocyte microfiber using anchoring device”
    Akiyo Yokomizo, Yuya Morimoto, Keigo Nishimura, Shoji Takeuchi
    Micromachines, vol. 10 (6), 358, 2019
  4. “Portable biohybrid odorant sensors using cell-laden collagen micropillars”
    Yusuke Hirata, Yuya Morimoto, Eunryel Nam, Shoji Takeuchi
    Lab on a Chip, vol. 19, pp. 1971-1976, 2019
  5. “Perfusable and stretchable 3D culture system for skin-equivalent”
    Nobuhito Mori, Yuya Morimoto, Shoji Takeuchi
    Biofabrication, vol. 11, 011001, 2019

2018

  1. “Three-dimensional printed microfluidic modules for design changeable coaxial microfluidic devices”
    Yuya Morimoto, Mahiro Kiyosawa, Shoji Takeuchi
    Sensors and Actuators B: Chemical, vol. 274, pp. 491-500, 2018
  2. “Biohybrid robot powered by an antagonistic pair of skeletal muscle tissues”
    Yuya Morimoto, Hiroaki Onoe, Shoji Takeuchi
    Science Robotics, vol. 3, pp. eaat4440, 2018, selected as the top cover of the issue, highlighted in Science
  3. “Three-dimensional contractile muscle tissue consisting of human skeletal myocyte cell line”
    Ai Shima, Yuya Morimoto, Hugh L. Sweeney, Shoji Takeuchi
    Experimental Cell Research, vol. 370 (1), pp. 168-173, 2018
  4. “Multipoint bending and shape retention of a pneumatic bending actuator by a variable stiffness endoskeleton”
    Shotaro Yoshida, Yuya Morimoto, Lanying Zheng, Hiroaki Onoe, and Shoji Takeuchi
    Soft Robotics, vol. 5 (6), pp. 718-725, 2018
  5. “Formation of branched and chained alginate microfibers using theta-glass capillaries”
    Keigo Nishimura, Yuya Morimoto, Nobuhito Mori, Shoji Takeuchi
    Micromachines, vol. 9, 303, 2018

2017

  1. “Mass production of cell-laden calcium alginate particles with centrifugal force”
    Yuya Morimoto, Maiko Onuki, Shoji Takeuchi
    Advanced Healthcare Materials, vol. 6, 1601375, 2017
  2. “Pesticide vapor sensing using an aptamer, nanopore, and agarose gel on a chip”
    Satoshi Fujii, Aiko Nobukawa, Toshihisa Osaki, Yuya Morimoto, Koki Kamiya, Nobuo Misawa, Shoji Takeuchi
    Lab on a chip, vol. 17, pp.2421-2425, 2017
  3. “Self-propelled motion of monodisperse underwater oil droplets formed by a microfluidic device”
    Naoko Ueno, Taisuke Banno, Arisa Asami, Yuki Kazayama, Yuya Morimoto, Toshihisa Osaki, Shoji Takeuchi, Hiroyuki Kitahara, Taro Toyota
    Langmuir, vol. 33, pp. 5393-5397, 2017
  4. “Skin integrated with perfusable vascular channels on a chip”
    Nobuhito Mori, Yuya Morimoto, Shoji Takeuchi
    Biomaterials, vol. 116, pp. 48-56, 2017

2016

  1. “Human induced pluripotent stem cell-derived fiber-shaped cardiac tissue on a chip”
    Yuya Morimoto, Saori Mori, Fusako Sakai, Shoji Takeuchi
    Lab on a Chip, vol. 16, pp. 2295-2301, 2016
  2. “Balloon Pump with Floating Valves for Portable Liquid Delivery”
    Yuya Morimoto, Yumi Mukouyama, Shohei Habasaki, Shoji Takeuchi
    Micromachines, vol. 7, 39, 2016
  3. “Vessel-like channels supported by poly-l-lysine tubes”
    Nobuhito Mori, Yuya Morimoto, Shoji Takeuchi
    vol. 122, pp. 753-757, 2016

2015

  1. “An inhalation anesthetic device for stereotaxic operation on mouse pups”
    Sachine Yoshida, Yuya Morimoto, Taishi Tonooka, Shoji Takeuchi
    Journal of Neuroscience Methods, vol. 243, pp. 63-67, 2015
  2. “Liquid-filled tunable lenticular lens”
    Yoshinobu Iimura, Hiroaki Onoe, Tetsuhiko Teshima, YunJung Heo, Shotaro Yoshida, Yuya Morimoto, Shoji Takeuchi
    Journal of Micromechanics and Microengineering, vol. 25, 035030, 2015

2013

  1. “Three-dimensional neuron-muscle constructs with neuromuscular junctions”
    Yuya Morimoto, Midori Kato-Negishi, Hiroaki Onoe, Shoji Takeuchi
    Biomaterials, vol. 34, pp. 9413-9419, 2013
  2. “Construction of 3D, Layered Skin, Microsized Tissues by Using Cell Beads for Cellular Function Analysis”
    Yuya Morimoto, Risa Tanaka, Shoji Takeuchi
    Advanced Healthcare Materials, vol. 2, pp. 261-265, 2013
  3. “Millimeter-Sized Neural Building Blocks for 3D heterogeneous Neural Network Assembly”
    Midori Kato-Negishi, Yuya Morimoto, Hiroaki Onoe, Shoji Takeuchi
    Advanced Healthcare Materials, vol. 2, pp. 1564-1570, 2013 selected as the front cover of the issue, highlighted on Materials views

2011

  1. “A hybrid axisymmetric flow-focusing device for monodisperse picoliter droplets”
    Yuya Morimoto, Kaori K.-Shigetomi, Shoji Takeuchi
    Journal of Micromechanics and Microengineering, vol. 21, pp. 054031, 2011
  2. “Molding cell beads for rapid construction of macroscopic 3D tissue architecture”
    (*equal contribution) Yukiko T.-Matsunaga*, Yuya Morimoto*, Shoji Takeuchi
    Advanced Materials, vol. 23, pp. H90-94, 2011, cover of the Advanced Healthcare Materials

2010

  1. “Monodisperse cell-encapsulating peptide microgel beads for 3D cell culture”
    Yukiko Tsuda, Yuya Morimoto and Shoji Takeuchi
    Langmuir, vol. 24, pp. 2645-2649, 2010

2009

  1. “Monodisperse semi-permeable microcapsules for continuous observation of cells”
    Yuya Morimoto, Wei-Heong Tan, Yukiko Tsuda, Shoji Takeuchi
    Lab on a Chip, vol. 9, pp. 2217-2223, 2009
  2. “Three-Dimensional Axisymmetric Flow-Focusing Device using Stereolithography”
    Yuya Morimoto, Wei-Heong Tan, Shoji Takeuchi
    Biomedical Microdevices, vol. 11, pp. 369-377, 2009

和文

  1. “培養骨格筋をアクチュエータとした泳動ロボットの作製”
    松下和磨, 森本雄矢, 竹内昌治
    日本機械学会論文集, vol. 86, no. 890, pp. 20-000180, 2020
  2. “簡易マイクロデバイス作製法”
    五條理保, 森本雄矢, 竹内昌治
    生物物理, vol. 50, pp. 38-41, 2010

総説

英文

  1. “Biohybrid softrobot driven by contractions of skeletal muscle tissue”
    Yuya Morimoto, Shoji Takeuchi
    Journal of Robotics and Mechatronics, vol. 34 (2), pp. 260-262, 2022
  2. “Biofabrication strategies for 3D in vitro models and regenerative medicine”
    Lorenzo Moroni, Jason Burdick, Christopher Highley, Sang Jin Lee, Yuya Morimoto, Shoji Takeuchi, James Yoo
    Nature reviews materials, vol. 3, pp. 21-37, 2018
  3. “Point-, line-, and plane-shaped cellular constructs for 3D tissue assembly”
    Yuya Morimoto, Amy Y. Hsiao, Shoji Takeuchi
    Advanced Drug Delivery Reviews, vol. 95, pp. 29-39, 2015
  4. “Three-dimensional cell culture based on microfluidic techniques to mimic living tissues”
    Yuya Morimoto, Shoji Takeuchi
    Biomaterials Science, vol. 1, pp. 257-264, 201

和文

  1. “細胞とマイクロデバイスの組み合わせによる生体模倣システムの構築”
    森本雄矢
    表面と真空, vol. 67 (9), pp. 433-438, 2024
  2. “生体機能を工学的に活かすバイオハイブリッドシステム”
    森本雄矢
    バイオメカニズム学会誌, vol. 48 (2), pp. 62-68, 2024
  3. “バイオハイブリッドソフトロボットの将来展望”
    森本雄矢
    日本ロボット学会誌, vol. 42 (6), pp. 19-22, 2024
  4. “培養組織×デバイスからなるバイオハイブリッドソフトロボット”
    森本雄矢
    電気学会誌, vol. 144 (3), pp. 144-147, 2024
  5. “バイオハイブリッドロボット—培養組織のロボティクスへの応用—”
    森本雄矢, 竹内昌治
    日本ロボット学会誌, vol. 39 (4), pp. 310-313, 2021
  6. “22.5 バイオ・医療MEMS”
    森本雄矢
    機械工学年鑑2020, online, 2020
  7. “23.5 バイオ・医療MEMS”
    森本雄矢
    機械工学年鑑2019, online, 2019
  8. “点・線・面形状の細胞ブロックを利用した3次元組織構築とその応用”
    森本雄矢, 竹内昌治
    電気学会論文誌E (センサ・マイクロマシン部門誌), vol. 137, pp. 322-327, 2017
  9. “骨格筋組織のin vitro構築”
    森本雄矢, 竹内昌治
    CLINICAL CALCIUM (医薬ジーナル社), vol. 27, pp. 383-389, 2017
  10. “立体組織は食肉になれるのか?”
    森本雄矢
    実験医学2015年5月号「医療・創薬に向けた立体臓器をつくる」(羊土社), vol. 33, pp. 1276-1277, 2015
  11. “細胞を用いた組織様構造の形成技術と医療への応用”
    森本雄矢, 竹内昌治
    実験医学増刊号「疾患克服をめざしたケミカルバイオロジー」(羊土社), vol. 30, pp. 1211-1219, 2012
  12. “バイオ材料を扱いやすくするビーズ化技術”
    津田行子, 森本雄矢, 竹内昌治
    月刊バイオインダストリー2009年12月号 (シーエムシー出版), vol. 26, No. 12, pp. 38-43, 2009

著書

英文

  1. “Chapter, Biological Material, Chapter, Soft Actuators”
    Yuya Morimoto, Shoji Takeuchi
    The Science of Soft Robot (Springer), 2023
  2. “Chapter 16, Biohybrid Robot Powered by Muscle Tissues”
    Yuya Morimoto, Shoji Takeuchi
    Mechanically Responsive Materials for Soft Robotics (Wiley), pp. 395-416, 2020
  3. “In vitro tissue construction for organ-on-a-chip application”
    Yuya Morimoto, Nobuhito Mori, Shoji Takeuchi
    Applications of Microfluidic Systems in Biology and Medicine (Springer), pp. 247-274, 2019
  4. “Chapter 21 Photo-Induced Fabrication Technology for 3D Microdevices”
    Daniela Serien, Yuya Morimoto, Shoji Takeuchi
    Advanced Mechatronics and MEMS Devices II (Springer), pp. 469-493, 2016
  5. “8. Microfluidic Formation of Cell-Laden Hydrogel Modules for Tissue Engineering”
    Yuya Morimoto, Yukiko T.-Matsunaga, Shoji Takeuchi
    Micro and Nanotechnologies in Engineering Stem Cells and Tissues (Wiley), pp. 183-201, 2013

和文

  1. “第5章7 身体運動を再現するバイオハイブリッドロボット”
    森本雄矢, 竹内昌治
    骨格筋研究を核とした筋スマート社会 (CMCリサーチ), pp. 241-247, 2019
  2. “第6章 細胞ファイバ技術を応用した3次元組織構築”
    根岸みどり, 森本雄矢, 竹内昌治
    再生医療・創薬のための3次元細胞培養技術 (シーエムシー出版), pp. 47-61, 2018
  3. “三次元組織構築”
    森本雄矢, 竹内昌治
    バイオマテリアル その基礎と先端研究への展開 (東京化学同人), pp. 341-344, 2016
  4. “MEMS技術を用いた三次元組織形成”
    森本雄矢, 竹内昌治
    三次元ティッシュエンジニアリング (エヌ・ティー・エス), pp. 293-300, 2015